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目的观察臭氧治疗复发性外阴阴道假丝酵母菌病(RVVC)的远期疗效,从真正意义上治愈RVVC。方法将揭阳市人民医院门诊收治的RVVC患者152例随机分为对照组76例,治疗组76例,对照组采用传统治疗,予克霉唑栓剂配伍氟康唑口服,治疗组予臭氧治疗配伍氟康唑口服,两组均分初步治疗和巩固治疗,从疗效及复发率比较两组患者的治疗效果。结果初步治疗:总有效率治疗组100%,对照组98.7%,P>0.05,差异无统计学意义;巩固治疗:总有效率治疗组100%,对照组96.1%,P>0.05,差异无统计学意义,但在全部治疗结束后半年观察远期疗效,比较两组的复发率,治疗组1.3%,对照组14.5%,P<0.05,差异有统计学意义。结论本研究证明臭氧治疗RVVC效果肯定,从真正意义上治愈了RVVC,且操作简单、安全、无副作用,具有很高的临床价值。
Objective To observe the long-term efficacy of ozone in the treatment of recurrent vulvovaginal candidiasis (RVVC) and to cure RVVC in the true sense. Methods Fifty-two RVVC patients admitted to Jieyang People’s Hospital were randomly divided into control group (n = 76) and treatment group (n = 76). The control group received traditional treatment with clotrimazole suppository and fluconazole. The treatment group was treated with ozone Conazole oral, two groups were divided into initial treatment and consolidation treatment, efficacy and relapse rate were compared between the two groups of patients. Results The initial treatment: the total effective rate of the treatment group 100%, 98.7% in the control group, P> 0.05, the difference was not statistically significant; consolidation therapy: total effective rate of 100% in the treatment group, 96.1% in the control group, P> 0.05, no difference However, the long-term curative effect was observed in half a year after the completion of all the treatments. The recurrence rate of the two groups was compared, 1.3% in the treatment group and 14.5% in the control group, P <0.05, the difference was statistically significant. Conclusion This study demonstrates that ozone treatment of RVVC positive effect, in a real sense of cure RVVC, and simple, safe, no side effects, with high clinical value.