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系统性红斑狼疮(SLE)是一种复杂的自身免疫性疾病,以自身抗体形成免疫复合物为特点,可伴有全身多器官炎症和广泛临床表型,其中皮肤科的症状表浅、特异,较易为医务工作者所掌握,但其他系统的临床表现错综复杂,极易误诊和漏诊。该文主要归纳总结了SLE在皮肤外各个系统的临床特征,包括黏膜、关节、心血管、肺、血液、消化道、肝脏、肾脏、浆膜等,旨在加深对此病的认识,提高SLE的诊治水平。
Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by autoantibodies forming immune complexes that may be associated with systemic multiple organ inflammation and a wide range of clinical phenotypes, with superficial, specific, Easier for medical workers to grasp, but the clinical manifestations of other systems intricate, easily misdiagnosed and missed diagnosis. This paper mainly summarizes the clinical features of SLE in various systems outside the skin, including mucosa, joint, cardiovascular, lung, blood, digestive tract, liver, kidney, serosa and so on, in order to deepen the understanding of the disease and improve SLE The level of diagnosis and treatment.