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凋亡是一种主动的细胞死亡,在围产期脑正常发育和缺血缺氧性脑损伤中起重要作用。本文对凋亡的特征、与坏死的关系、凋亡在围产期脑正常发育及缺血缺氧性脑损伤中的作用、脑细胞凋亡的治疗等方面的研究进展进行综述。
Apoptosis is an active cell death that plays an important role in normal perinatal brain development and hypoxic-ischemic brain damage. This article reviews the characteristics of apoptosis, the relationship with necrosis, the role of apoptosis in the normal development of perinatal brain and the role of cerebral ischemia and hypoxia in the treatment of cerebral apoptosis.