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目的探讨克龄蒙治疗围绝经期综合征的临床疗效。方法选取2013年我院围绝经期健康女性30例,30例对象均有围绝经期临床表现,另选取在我院体检健康、月经规则的健康生育期女性50例作为对照组。每天口服克龄蒙1片,连服21天,治疗3个月后对30例患者进行Kupperman评分,并检测血卵泡刺激素(FSH)、雌二醇(E2)与服药前后子宫内膜厚度。结果患者治疗前后K评分、血FSH下降明显,E2升高明显,子宫内膜厚度增厚,评价指标具有统计学意义。结论克龄蒙能有效缓解围绝经期综合征症状,疗效较好,具有重要的临床应用价值。
Objective To investigate the clinical efficacy of Kelinmeng in treating perimenopausal syndrome. Methods Thirty patients with peri-menopausal healthy women in our hospital from 2013 were selected. All 30 patients had perimenopausal clinical manifestations. Another 50 healthy women with healthy menstruation and physical examination in our hospital were selected as control group. Ketamine was administered orally once a day for 21 consecutive days. Kupperman scores were measured in 30 patients after 3 months of treatment. The levels of FSH, E2 and the thickness of endometrium before and after treatment were measured. Results Before and after treatment K score, blood FSH decreased significantly, E2 increased significantly, thickening of the endometrium, the evaluation index was statistically significant. Conclusion Kelin Meng can effectively alleviate the symptoms of perimenopausal syndrome, the effect is good, has important clinical value.