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肝硬化门脉高压症病人外周的血细胞数量减少在临床上很普遍,并常常影响到预后。本文探讨肝硬化门脉高压症病人并发外周血细胞数量减少的原因以及这些原因有何临床意义,从而为治疗方式的选择提供理论支撑。脾肿大或脾机能亢进是引起血细胞减少的主要原因,但不是全部,其他原因还有酒精及病毒对骨髓的抑制作用,肝功能减退,自身免疫受损,失血等。如果是脾功能亢进引起的血细胞减少,脾切除术后血细胞应该上升至正常,否则就要考虑其他原因或同时存在其他原因。重度外周血细胞数量减少应行脾切除术。
The reduction in the number of peripheral blood cells in patients with cirrhosis and portal hypertension is clinically common and often affects prognosis. This article explores the reasons for the decrease in the number of peripheral blood cells in patients with cirrhosis and portal hypertension and the clinical significance of these reasons, thus providing theoretical support for the choice of treatment. Splenomegaly or hypersplenism is the main cause of cytopenia, but not all, other reasons are alcohol and virus inhibition of bone marrow, liver dysfunction, autoimmune damage, blood loss and so on. If the cytopenia caused by hypersplenism, after splenectomy, blood cells should rise to normal, otherwise we must consider other reasons or other reasons at the same time. Severe reduction of peripheral blood cells should be splenectomy.