本文以雷氏盐(Reinecke salt)与盐酸利多卡因所形成的缔合物为电活性材料,以 DNP 为增塑剂,制成了全固态石墨涂膜电极(A)和铜基体涂膜电极(B)。所制的两类电极对电位响应快速、稳定,其 Nernst 线性范围分别为1×10~(-1)～6.31×10~(-6)M 和1×10~(-1)～1×10~(-5)M,电极的 Nernst 斜率分别为53.34 mV·decade~(-1)和55.16mV·decade~(-1)(20℃),pH 适用范围分别为5～8和4～7;同时,两类电极对盐酸利多卡因都具有良好的选择性,用双标准加入法测得两类电极的测定回收率分别为100.4%和100.2%;对医用针剂中盐酸利多卡因含量的测定,分析结果与用药典法测定的结果基本相符. In this paper, the association of Reinecke salt and lidocaine hydrochloride was used as the electroactive material, DNP was used as the plasticizer to prepare the all-solid graphite coating electrode (A) and the copper matrix coating electrode (B). The potentials of the two kinds of electrodes are fast and stable, and the linear ranges of Nernst are 1 × 10 -1 ~ 6.31 × 10 -6 M and 1 × 10 -1 -1 × 10 ~ (-5) M, the Nernst slopes of the electrodes are 53.34 mV · decade -1 and 55.16 mV · decade -1 (20 ℃), respectively, and the pH ranges are 5 ~ 8 and 4 ~ 7 respectively. At the same time, the two types of electrodes have good selectivity for lidocaine hydrochloride. The recoveries of two kinds of electrodes measured by double standard addition method were 100.4% and 100.2% respectively. The determination of lidocaine hydrochloride in medical injections , The results of the analysis are basically consistent with the results of pharmacopoeia.