Toll样受体(Toll-like receptors,TLRs)是近年来新发现的一种同源于果蝇Toll的蛋白分子,属于Ⅰ型跨膜蛋白受体,自从研究者首先发现人类Toll样受体,目前其家族成员至少有11个[1]。TLR能够对病原体识别、结合、引发一系列信号间的转导,促进各种炎性介质的释放,在早期启动固有免疫 Toll-like receptors (Toll-like receptors, TLRs) is a new type of protein homologue to Drosophila Toll, which belongs to the type I transmembrane protein receptor. Since the researchers first discovered that human Toll-like receptors, At present, at least 11 of its family members [1]. TLRs recognize, bind to, trigger a series of signal transduction pathways and promote the release of various inflammatory mediators, initiating innate immunity early