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目的分析新生儿缺氧缺血性心肌损伤的临床表现、辅助检查及治疗方法,以期提高临床诊治水平。方法选择足月新生儿缺氧缺血性脑病合并心肌损伤患儿60例为研究对象,对其临床表现、辅助检查和治疗情况进行观察。结果新生儿缺氧缺血性脑病合并心肌损伤以面色苍白、紫绀、皮肤花纹、心音低钝、心动过缓或过速、心律不齐等为主要临床表现,辅助检查以心电图和心肌酶谱改变为主,综合治疗基础上,加用磷酸肌酸钠等改善心肌治疗后,治愈55例(91.67%),好转4例(6.67%),死亡1例(1.67%)。结论新生儿缺氧缺血性心肌损伤是可逆的,经临床积极治疗,心肌酶谱多可恢复正常,往往不遗留心脏功能后遗症。
Objective To analyze the clinical manifestations of neonatal hypoxic-ischemic myocardial injury, and to assist in the examination and treatment of the disease in order to improve the level of clinical diagnosis and treatment. Methods Sixty infants with full-term neonatal hypoxic-ischemic encephalopathy complicated with myocardial injury were selected as the study object, and their clinical manifestations, auxiliary examinations and treatment were observed. Results Neonatal hypoxic-ischemic encephalopathy with myocardial injury with pale, cyanotic, skin pattern, low heart sound blunt, bradycardia or tachycardia, arrhythmia as the main clinical manifestations, auxiliary examination with ECG and myocardial enzyme changes (91.67%), improvement in 4 cases (6.67%), and death in 1 case (1.67%), based on the comprehensive treatment and the addition of sodium creatine phosphate. Conclusions Neonatal hypoxic-ischemic myocardial injury is reversible. After active clinical treatment, myocardial enzymes can resume normal, often without leaving sequelae of cardiac function.