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目的 探讨孕妇C反应蛋白(CRP)、白介素-6(IL-6)、中性粒-淋巴细胞比值(NLR)及血小板-淋巴细胞比值(PLR)在妊娠剧吐(HG)中的关系及意义.方法 随机抽取2014年1月至2016年6月在本院就诊的100例HG孕妇为研究组,100例健康孕妇为对照组,对两组临床资料进行回顾性分析.结果 研究组IL-6、CRP、NLR、PLR及乳酸脱氢酶(LDH)水平均明显高于对照组,差异有统计学意义(P<0.05).CRP、IL-6与妊娠剧吐的严重程度呈正相关,F值分别为235.141和79.624,差异有统计学意义(P<0.05).NLR和PLR数值与炎症因子CRP、IL-6的水平均无明显关联性.NLR及PLR的cutoff值分别为2.51、130.81.结论 HG的发生发展与炎症机制有着密切关系,NLR及PLR水平或许可用于妊娠剧吐的预测.“,”Objective To investigate the relationship between serum C-reactive protein (CRP),interleukin-6 (IL-6), neutrophil-lymphocyte ratio(NLR)and platelet-lymphocyte ratio(PLR)in hyperemesis gravidarum(HG)pregnant woman. Methods 100 pregnant women diagnosed of HG and 100 healthy pregnant women in our hospital were selected for retrospective analysis from January 2014 to June 2016. Results The levels of IL-6,CRP,NLR,PLR and lactate dehydrogenase(LDH)in the study group were significantly higher than those in the control group(P<0.05). The levels of CRP and IL-6 were positively correlated with the severity of HG with F values of 235.141 and 79.624,respectively(P<0.05). There was no significant correlation between NLR and PLR values and levels of CRP and IL-6. The cutoff values of NLR and PLR were 2.51 and 130.81,respectively. Conclusion The development of HG was closely related to the mechanism of inflammation ,and NLR and PLR could be used for predicting HG.