目的观察并探究针对早期乳腺癌患者实施保留乳头乳晕改良根治术联合假体置入术治疗的效果。方法 90例早期乳腺癌患者,分为研究组与参照组,各45例。参照组予以传统改良根治术,研究组予以保留乳头乳晕改良根治术联合假体置入术,观察比较两组疗效。结果术后4个月观察,研究组乳房外观优良率为97.78%,优于参照组的66.67%(P<0.05);两组并发症情况比较差异无统计学意义(P>0.05);术后18个月随访,两组肿瘤转移率比较差异无统计学意义(P>0.05)。结论针对早期乳腺癌患者实施保留乳头乳晕改良根治术联合假体置入术治疗,美容效果较为理想,有广泛应用的价值。 Objective To observe and investigate the effect of modified radical mastectomy combined with prosthesis implantation in patients with early stage breast cancer. Methods 90 cases of early breast cancer patients were divided into study group and reference group, 45 cases in each. The reference group was given the traditional modified radical mastectomy, and the study group was to retain the nipple-arena modified radical mastectomy combined with prosthesis implantation. The curative effect was observed and compared between the two groups. Results At 4 months after operation, the excellent and good rate of breast appearance was 97.78% in the study group, which was better than 66.67% of the reference group (P <0.05). There was no significant difference in the complication between the two groups (P> 0.05) At 18-month follow-up, there was no significant difference in tumor metastasis between the two groups (P> 0.05). Conclusion For the patients with early stage breast cancer, the conservative modified nipple-nipple surgery combined with prosthesis implantation has better cosmetic effect and wider application value.