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目的:通过对使用双环醇片儿童用药的分析,了解患儿的临床特征,找到联合用药最佳方案。方法:连续纳入全国18家三甲综合医院信息系统的476例使用双环醇片的患儿,采用频数分析和关联规则分析方法,登记和分析患儿的一般情况和联合用药情况。结果:476例使用双环醇患儿年龄高峰为0-3岁,使用男性大于女性,男女比例为2∶1。发病以消化系统疾病为主,排名前3位疾病为病毒性肝炎、肝硬化、黄疸。联合西药多于联合中药,以联合甘草酸注射剂辅助其他药剂提高疗效明显。结论:双环醇片以治疗儿童消化系统肝胆疾病为主,为提高疗效,建议联合清热祛湿中药甘草酸注射剂,儿童服用双环醇片需注意规范用药。
OBJECTIVE: To understand the clinical characteristics of children through the analysis of children’s medication using bicyclic alcohol tablets and to find the best combination of drugs. Methods: A total of 476 children with bicyclol tablets, which were continuously included in the information system of 18 KPA hospitals in the country, were enrolled in this study. The frequency and association rules were used to register and analyze the general situation and the combination of medication in children. Results: The age of 476 children with bicyclol was 0-3 years old. The male was more than the female, the ratio of male to female was 2: 1. The incidence of digestive diseases, the top three diseases for viral hepatitis, cirrhosis, jaundice. Western medicine more than combined with traditional Chinese medicine, combined with glycyrrhizin injection to help other agents to improve the curative effect. CONCLUSION: Bicyclomethanol tablets are mainly used to treat hepatogastric diseases of children’s digestive system. In order to improve the curative effect, it is recommended to combine licorice acid injection with heat-clearing and damp-proofing Chinese medicine. Children taking bicyclol tablets should pay attention to standard medication.