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为了评价测定周围血浆中LHRH的意义,作者在具有不同内分泌情况的妇女中测定血浆LHRH免疫反应和促性腺激素。对象为198名年龄18~71岁妇女。89人是有规则月经周期的健康妇女,其中43人在卵泡期;34人在黄体期;12人有LH峰,在排卵期周围。54人为功能性闭经:18人促性腺激素低下;26人促性腺激素正常;10人促性腺激素过高。14人为绝经后妇女。21人为多囊卵巢综合征。6人为Turner氏综合征。5人为席汉氏综合征。9人为去势妇女,其中7人去势后每周1或2次取血样,检查血浆LHRH免疫反应的变化。
To evaluate the significance of determining LHRH in peripheral plasma, the authors measured plasma LHRH immune response and gonadotropin in women with different endocrine conditions. The object is 198 women aged 18 to 71 years. 89 are healthy women with regular menstrual cycles, 43 of whom are in follicular phase; 34 in luteal phase; and 12 have LH peak around ovulation period. 54 were functional amenorrhea: 18 were low in gonadotropins; 26 were normal in gonadotropins; 10 were hypersensitive to gonadotropins. 14 are postmenopausal women. 21 were polycystic ovary syndrome. Six people are Turner’s syndrome. 5 people for Shenton’s syndrome. Nine were castrated women. Seven of them took blood sample 1 or 2 times a week after castration to check the change of LHRH immune response in plasma.