背景 多发性硬化症(MS)是一种复发性或进行性神经脱离髓鞘性疾病。已有资料显示,血浆置换(TPE)有助于控制患者快速进行性发展的病情。材料与方法 作者回顾性分析了过去8个月里以TPE治疗的4例MS。其中3例患者每次以一单位血浆进行TPE,共7次TPE治疗。1例实施了5次TPE,未完成余下的TPE(非医学原因)。1例患者进行了另一疗程7次TPE。前两次TPE为连续两天完成,以后时间隔7天。采用Kurtzke’s Background Multiple sclerosis (MS) is a recurrent or progressive neurological demyelinating disease. It has been shown that plasma exchange (TPE) can help control the rapid progression of patients. Materials and Methods The authors retrospectively reviewed 4 MS patients treated with TPE in the past 8 months. Three of these patients underwent TPE in one unit of plasma each time, for a total of seven TPE treatments. One case had TPE 5 times and the remaining TPE was not completed (non-medical cause). One patient underwent another 7 courses of TPE. The first two TPEs were completed in two consecutive days, after a lapse of seven days. Using Kurtzke’s