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目的探讨介入溶栓术治疗急性闭塞性脑梗死的最佳时机。方法将急性闭塞性脑梗死患者200例随机分为试验组和对照组各100例,试验组患者在发病3h以内进行手术,对照组患者在发病3~6h进行手术,治疗结束后对比2组患者的临床疗效及NIHSS神经评分。结果试验组总有效率高于对照组,差异有统计学意义(P<0.05)。2组患者术前及术毕NIHSS评分比较差异均无统计学意义(P>0.05),2组患者术后24h、术后7d及术后21d NIHSS评分均显著降低,且试验组低于对照组,差异均有统计学意义(P<0.05)。结论介入溶栓术治疗急性闭塞性脑梗死患者发病时间越短治疗效果越好,利于患者闭塞再次打通,见效快效果好。
Objective To investigate the best timing of interventional thrombolysis in the treatment of acute occlusive cerebral infarction. Methods 200 patients with acute occlusive cerebral infarction were randomly divided into experimental group and control group with 100 cases in each group. Patients in the experimental group were operated within 3 hours after onset of disease. Patients in the control group were operated from 3 to 6 hours after onset. After the treatment, The clinical efficacy and NIHSS nerve score. Results The total effective rate of the experimental group was higher than that of the control group, with statistical significance (P <0.05). There was no significant difference in NIHSS score between the two groups (P> 0.05). The scores of NIHSS at 24h, 7h and 21d after operation in both groups were significantly lower than those in control group , The differences were statistically significant (P <0.05). Conclusion Interventional thrombolysis in patients with acute obstructive cerebral infarction onset time is shorter, the better the treatment effect, which will help patients occlusion reopened, effective quick results.