据《欧洲分子生物学会杂志》(EMBO)报道,组蛋白去乙酰化酶(HDAC)可减少RNA聚合酶的补充及HIV转录的启动,促进HIV的T细胞内潜伏。来自于旧金山加州大学的Warner C．Greene博士报道说,解决HIV的潜伏问题的确非常困难,但只要进一步了解HIV潜伏的分子基础,人类就可将HIV病毒从潜伏的宿主细胞中彻底清除出去。Greene博士及其同事利用J-Lat HIV潜伏的人 According to the EMBO report, histone deacetylases (HDACs) reduce RNA polymerase replenishment and initiation of HIV transcription and contribute to HIV T cell lurking. From Warner C at the University of California, San Francisco. Dr. Greene reports that it is indeed very difficult to solve the latent problem of HIV. However, as long as we further understand the molecular basis of latent HIV, humans can completely eliminate the HIV virus from the latent host cells. Dr. Greene and colleagues use J-Lat HIV latent people