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目的:探讨急性脑外伤纳洛酮的治疗效果。方法:选择我院2011年1月至2012年1月收治的急性脑外伤患者30例,在常规治疗的基础上加用纳洛酮治疗(观察组),就临床资料与同期收治的单纯行常规治疗的同类型患者30例(对照组)进行比较。结果:观察组治疗后呼吸异常、心电图异常情况显著低于对照组,差异有统计学意义(P<0.05)。两组颅内压、GCS评分治疗前无明显差异,治疗后观察组颅内压和GCS评分均优于对照组(P<0.05),且恢复情况显著优于对照组(P<0.05)。结论:急性脑外伤采用纳洛酮治疗,可对患者的呼吸及血压起到稳定作用,使意识障碍得到改善,对神经功能的恢复起到促进作用,显著提高了患者的生活质量。
Objective: To investigate the therapeutic effect of naloxone on acute brain injury. Methods: Thirty patients with acute traumatic brain injury admitted to our hospital from January 2011 to January 2012 were selected and treated with naloxone on the basis of routine treatment (observation group). The clinical data and routine treatment The same type of patients treated 30 cases (control group) were compared. Results: After treatment, the abnormal breathing and electrocardiogram abnormalities in the observation group were significantly lower than those in the control group (P <0.05). The intracranial pressure and GCS score of the two groups had no significant difference before treatment. After treatment, the intracranial pressure and GCS score of the observation group were better than the control group (P <0.05), and the recovery was significantly better than that of the control group (P <0.05). Conclusion: Naloxone treatment of acute traumatic brain injury can stabilize respiration and blood pressure of patients, improve the disturbance of consciousness, promote the recovery of nerve function, and significantly improve the quality of life of patients.