大气颗粒物与呼吸系统疾病、心血管系统疾病及肿瘤等密切相关。其中,哮喘因其影响的广泛性和病因的复杂性逐渐成为研究的热点。DC、Th2和Treg 3种细胞在哮喘的免疫应答调控中起着重要作用,但是大气颗粒物诱发哮喘的过程中,DC、Th2和Treg及相关效应分子等的免疫应答机制尚不清楚。本文综述了大气颗粒物诱发哮喘的研究进展,并探讨了其可能的免疫调控机制。 Atmospheric particulate matter is closely related to respiratory diseases, cardiovascular system diseases and tumors. Among them, asthma due to its wide range of effects and the complexity of the cause has gradually become the focus of research. The three kinds of cells, DC, Th2 and Treg, play an important role in the regulation of asthma immune response. However, the mechanisms of immune response such as DC, Th2 and Treg and related effector molecules are not yet clear in the process of airborne particle-induced asthma. This review summarizes the research progress of atmospheric particulate matter-induced asthma and explores its possible mechanism of immune regulation.