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妊娠与正常肝脏妊娠期由于胎儿生长发育的需要,母体各器官发生了一系列的适应性生理变化,肝脏也不例外,肝功能一般无改变。通过光镜和电镜的观察仅在肝细胞中有糖原含量的增加和脂肪的累积。大多数肝脏不能触及,也无压痛,但肝血流量相对降低。在正常妊娠期呈现出:(1)轻度胆汁郁积和血清胆酸轻度升高;(2)肝排泄功能失常;(3)胆囊呈低张性扩张,胆汁粘稠,推迟了排空时间;(4)妊娠晚期部分生化指标有改变,如:血清蛋白浓度降低至6g/dl以下,丙种球蛋白也轻度降低;血清胆固醇可升高至300mg/dl,血胆红素增高至1mg/dl;血清碱性磷酸酶增高1倍多;血清谷丙转氨酶(SGPT)和谷草转氨酶(SGOT)正常,但接近分娩期可增高至
Pregnancy and normal liver Pregnancy due to the needs of fetal growth and development, the maternal organs of a series of adaptive physiological changes occurred, the liver is no exception, the liver function generally no change. Observations by light and electron microscopy showed an increase in glycogen content and accumulation of fat only in hepatocytes. Most of the liver can not be touched, nor tender, but the relative decrease in hepatic blood flow. In normal pregnancy, there are: (1) mild cholestasis and mild increase in serum bile acid; (2) dysfunction of liver excretion; (3) gallbladder was dilated dilated, bile viscous, delayed the emptying time ; (4) changes in some biochemical indicators of late pregnancy, such as: serum protein concentration decreased to 6g / dl less gamma globulin also slightly lower; serum cholesterol can be increased to 300mg / dl, elevated serum bilirubin to 1mg / dl; serum alkaline phosphatase increased more than 1 times; serum alanine aminotransferase (SGPT) and aspartate aminotransferase (SGOT) normal, but close to childbirth can be increased to