下肢急性缺血后血管再通的死亡率和并发症意外地高。过去曾将其归因于外科损伤、原有的心血管疾病、复发性血栓形成和肺拴塞等,但也有人提出缺血肌肉在血管再通后可释放毒素损害肺、心、肾和肝。鉴于肢体血流再通后的死亡率高于未通者,缺血肌肉的重新灌注似乎对肌间室综合症、肌球蛋白尿、肾功能衰竭、再栓塞、肢体丧失、心肌抑制以致死亡的发生有重要作用。 Mortality and complications of recanalization after acute ischemia of the lower limbs are unexpectedly high. In the past it has been attributed to surgical injury, the original cardiovascular disease, recurrent thrombosis and pulmonary embolism, but it was also suggested that muscles can release toxins after revascularization of the lungs, heart, kidney and liver . In view of the higher mortality rate after limbal recanalization, the reperfusion of ischemic muscle seems to be the cause of death in compartment syndrome, myosinuria, renal failure, re-embolization, limb loss, and myocardial suppression Occurrence has an important role.