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本文采用胃癌单克隆抗体斑点试剂盒对127例住院及门诊患者进行胃癌抗原检测与胃镜病理做对照,真阳性9例,真阴性56例假阳性62例,其敏感性100%,正确性为51.18%,阳性预测值为12.1%,无漏诊病人。对胃癌及非胃癌组,胃癌前病变与良性病进行X ̄2检验均有显著性差别,因此可用于胃癌大面积普查及门诊筛检。本组检验胃癌与癌前病变无显著性差别,这可能与癌前病变分泌的糖蛋白有交叉反应,本文对假阳性的原因进行了探讨。
In this study, gastric cancer antigen detection and gastroscope pathology were used to compare 127 cases of inpatients and outpatients with gastric cancer monoclonal antibody spot kit. There were 9 true positive cases and 56 true false negative cases. The sensitivity was 100%, and the correctness was 51. 18%, positive predictive value was 12.1%, no missed patient. For the gastric cancer and non-gastric cancer groups, the X ̄ 2 test for precancerous lesions and benign diseases was significantly different. Therefore, it can be used for large-scale gastric cancer screening and outpatient screening. There was no significant difference between gastric cancer and precancerous lesions in this group. This may have cross-reactions with glycoproteins secreted by precancerous lesions. This article discusses the causes of false positives.