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本文对100例直肠息肉进行了病理分析,对三型常见息肉中上皮不典型增生分为Ⅰ—Ⅲ级,并提出分级的标准。也指出Ⅲ级不典型增生与癌重叠所致的鉴别困难。100例息肉中癌变17例,其中13例绒毛状息肉癌变率最高(53.8%),这提示对绒毛状息肉应注意详细组织学检查,有无息肉癌变。息肉癌变形式见到微小癌,灶性癌两种,区别两者有利于估计预后及治疗。Ⅲ级不典型增生为狭义的癌前病变,与癌之间并无明确界限,需根据组织结构与癌细胞异型性以及两者的关系综合判断。
In this paper, pathological analysis of 100 cases of rectal polyps was carried out. The dysplasia of the three types of common polyps was divided into grades I-III, and grading standards were proposed. It also points out the difficulty in distinguishing grade III dysplasia from cancer overlap. Among the 100 cases of polyposis, 17 cases were cancerous, of which 13 cases had the highest rate of malignant transformation of villous polyps (53.8%). This suggests that attention should be paid to the detailed histological examination of villous polyps and the presence or absence of polyposis. Polyposis can be seen in the form of small cancers, two types of focal cancer, the difference between the two is conducive to the evaluation of prognosis and treatment. Grade III atypical hyperplasia is a precancerous lesion in a narrow sense. There is no definite boundary between carcinoma and cancer. It needs to be judged comprehensively based on the relationship between the histological structure and the heterogeneity of cancer cells and the relationship between them.