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From February 1995 to March 1999, compared by 108 patients treated by west medicine, 120 patients suffering from chronic eczema on their hands have been treated by the authors with modified Weiling Decoction (WLD) and the therapeutical effects observed. The results are reported as follows.rnMETHODSrnClinical Datarn All the patients who suffered from eczema on hands were outpatients and were tested by local squamous fungus culture before treatment, with the results negative, and conformed to the diagnostic standards of eczema in “Clinical Dermatology”(2nd edition, Nanjing, Jiangsu Science and Technology Press. 1999∶512-515). The patients were divided into the treated group and the control group. There were 120 patients in the treated group, 56 males and 64 females, their age ranging from 24 to 64 years, mean age 44 years; the illness course were 1-12 years, mean course 6.5 years, 35 of the patients were accompanied with eczema on other parts of the body or nail change. At the same time there were 108 patients in the control group, 46 males and 62 females; their age ranging from 18 to 56 years, mean age 37 years; the illness course ranging from 3 to 10 years , mean course 6.5 years, 38 of the cases were accompanied with eczema on other parts of the body or with nail change. Statistical analysis indicated that the two groups were comparable.