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目的对48例子宫肌瘤患者采用药物治疗方法的临床效果予以分析研究。方法 48例子宫肌瘤患者,根据患者就诊顺序随机分为A、B、C三组,各16例。A组给予米非司酮,B组给予三苯氧胺,C组给予丹那唑,观察比较三组患者用药前后子宫体积和肌瘤体积的改变情况。结果三组患者药物治疗后子宫体积及肌瘤体积均小于治疗前,差异有统计学意义(P<0.05)。治疗后A组子宫体积缩小程度为53.1%,肌瘤体积缩小程度为50.0%;B组子宫体积缩小程度为34.3%,肌瘤体积缩小程度为26.8%;C组子宫体积缩小程度为34.8%,肌瘤体积缩小程度为30.0%。治疗后A组患者子宫体积和肌瘤体积缩小程度最高。结论和治疗前患者的身体状况相比,在经过药物治疗后,患者的身体状况较好,且没有特别严重的不良反应,其中,使用米非司酮药物对子宫肌瘤进行治疗后,子宫体积和肌瘤体积的缩小程度最高,值得在临床上推广应用。
Objective To analyze the clinical effect of 48 cases of uterine fibroids treated by drug therapy. Methods 48 patients with uterine fibroids, according to the order of patients were randomly divided into A, B, C three groups, each 16 cases. Group A was given mifepristone, group B was given tamoxifen, and group C was given danazol. The changes of uterine volume and fibroid volume before and after treatment were observed and compared in three groups. Results After treatment, the uterine volume and fibroid volume of the three groups were all less than those before treatment, the difference was statistically significant (P <0.05). After treatment, the size of uterus in group A was reduced by 53.1% and the size of fibroids was reduced by 50.0%. In group B, the reduction of uterine volume was 34.3% and that of fibroids was reduced by 26.8%. In group C, the reduction of uterine volume was 34.8% Myoma size reduction of 30.0%. A group of patients after treatment, the volume of uterine fibroids and the largest shrinkage. Conclusion Compared with the physical condition of patients before treatment, after the medical treatment, the patient’s physical condition is better, and there is no particularly serious adverse reactions, of which, the use of mifepristone treatment of uterine fibroids, uterine volume And fibroids shrink the highest volume, it is worth to promote the clinical application.