论文部分内容阅读
目的 :在制备大鼠胰源性肺损伤动物模型基础上给予中药治疗 ,动态观察血氧分压及二氧化碳分压变化 ,并对肺脏进行病理学分析。 方法 :实验分为模型组及中药治疗组 ,72h后观察肺脏病理变化及不同时间血气分析。 结果 :治疗组肺脏病理改变明显减轻 (P <0 0 5 ) ;治疗组 72h血氧分压明显高于模型组 (P <0 0 1) ,血二氧化碳分压明显低于模型组 (P <0 0 1)。 结论 :在胰源性肺损伤发病过程中 ,血氧分压及二氧化碳分压的变化直接反应出肺损伤病理改变的严重程度 ,治疗组随着氧分压升高 ,二氧化碳分压降低 ,标志着肺脏病理改变明显减轻。
OBJECTIVE : To treat the animal model of pancreatic lung injury by the preparation of rat animal model of pancreatic lung injury, dynamically observe the change of blood oxygen partial pressure and carbon dioxide partial pressure, and perform pathological analysis of the lung. Methods : The experiment was divided into model group and traditional Chinese medicine treatment group. The pathological changes of lung and blood gas analysis at different time were observed after 72 hours. Results: The pathological changes of the lungs in the treatment group were significantly reduced (P < 0.05). The oxygen partial pressure in the treatment group was significantly higher than that in the model group (P <0 01) at 72 hours, and the partial pressure of blood carbon dioxide was significantly lower than that in the model group (P <0). 0 1). Conclusion: During the pathogenesis of pancreatic lung injury, changes in partial pressure of blood oxygen and partial pressure of carbon dioxide directly reflect the severity of pathological changes in lung injury. In the treatment group, the partial pressure of carbon dioxide decreases with increasing oxygen partial pressure, indicating that Pathological changes in the lung were significantly reduced.