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目的探讨无创呼吸机联合间断特布他林雾化治疗慢性阻塞性肺疾病合并呼吸衰竭的临床疗效。方法回顾性分析慢性阻塞性肺疾病合并呼吸衰竭60例患者的治疗资料。将60例随机分为两组,均应用解痉平喘、化痰、抗感染、维持水电解质平衡等常规方法治疗。治疗组在常规治疗的基础上应用无创面罩呼吸机及间断特布他林雾化治疗。观察两组患者治疗前及治疗后24、72 h的动脉血气分析变化情况。结果治疗组各临床指标均改善,明显优于对照组,两组比较差异有统计学意义(P<0.05)。结论应用无创面罩呼吸机及间断特布他林雾化治疗慢性阻塞性肺疾病合并呼吸衰竭,可纠正低氧血症及高碳酸血症,明显缩短治疗时间,操作简单,无创伤、感觉舒适,更容易被患者、家属所接受,值得临床推广。
Objective To investigate the clinical efficacy of noninvasive ventilator combined with intermittent terbutaline in the treatment of chronic obstructive pulmonary disease with respiratory failure. Methods The clinical data of 60 patients with chronic obstructive pulmonary disease and respiratory failure were retrospectively analyzed. Sixty patients were randomly divided into two groups, all using spasm and asthma, phlegm, anti-infection, water and electrolyte balance to maintain conventional methods of treatment. On the basis of routine treatment, the treatment group was treated with non-invasive mask ventilator and intermittent terbutaline atomization. Arterial blood gas analysis before and 24,72 h after treatment was observed in two groups of patients. Results All the clinical indexes in the treatment group were improved, which were obviously better than those in the control group. There was significant difference between the two groups (P <0.05). Conclusion The application of noninvasive mask ventilator and discontinuous terbutaline atomization in the treatment of chronic obstructive pulmonary disease combined with respiratory failure can correct hypoxemia and hypercapnia, shorten the treatment time, simple operation, no trauma, feel comfortable, Easier to be accepted by patients and their families, worthy of clinical promotion.