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目的分析基层接种门诊疑似预防接种异常反应(AEFI)的发生情况,探讨基层接种门诊减少AEFI发生的应对措施。方法收集2008─2014年新疆医科大学第五附属医院发生AEFI的登记表、月报表、个案调查表、一类和二类疫苗使用情况登记表的相关数据,并进行描述性分析。结果 2008─2014年共报告AEFI病例563例,报告发生率为133.06/10万,其中一般反应510例(占90.59%)、异常反应34例(占6.04%)、偶合症19例(占3.34%);报告病例数最多年份为2011年111例、发生率136.96/10万,2014年最低32例、发生率为44.85/10万;报告发生率最高年份为2009年377.00/10万;除2009年开展主动监测AEFI发生率较2008年高外,2010─2014年AEFI发生率均较2008年下降。结论采取综合性防控措施,可有效降低AEFI的发生率,消除公众对预防接种的抵触心理,保护易感人群。
Objective To analyze the occurrence of suspected AEFI in primary vaccination clinics and to explore the measures to reduce the occurrence of AEFI in primary vaccination clinics. Methods The data of AEFI registration form, monthly report, case investigation form, class I and II vaccines registration form from the fifth affiliated hospital of Xinjiang Medical University from 2008 to 2014 were collected and analyzed descriptively. Results A total of 563 AEFI cases were reported from 2008 to 2014, with a reported incidence of 133.06 / 100 000, of which 510 cases (90.59%) were general reactions, 34 cases (6.04%) were abnormal reactions, 19 cases (3.34% ); The highest number of reported cases in 2011 was 111 cases, the incidence was 136.96 / 100000, the lowest in 32 cases in 2014, the incidence was 44.85 / 100000; the highest reported incidence in 2009 377.00 / 100000; except in 2009 The number of AEFIs monitored voluntarily was higher than that of 2008, and the incidence of AEFI during 2010-2014 decreased from 2008. Conclusion The comprehensive prevention and control measures can effectively reduce the incidence of AEFI, eliminate the public’s psychological confusion of vaccination and protect the susceptible population.