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应用单细胞凝胶电泳技术(彗星实验)检测了3种典型醛类污染物对小鼠脾淋巴细胞DNA损伤情况。结果发现3种化合物都引起了小鼠脾淋巴细胞产生彗星现象,并且存在一定的剂量-效应关系。表明此3种醛类化合物均可引起细胞DNA发生断裂
Single cell gel electrophoresis (comet assay) was used to detect the DNA damage of three typical aldehydes in mice splenic lymphocytes. The results showed that all three compounds caused comet phenomenon in mouse splenic lymphocytes, and there was a certain dose-effect relationship. These three kinds of aldehyde compounds can cause cell DNA to be broken