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采用斑点杂交（Ｄｏｔｂｌｏｔ）对１０例人原发性肝癌和癌周肝组织中的ＨＳＵ１７７１４基因的ｍＲＮＡ表达进行了比较研究。结果表明，ＨＳＵ１７７１４基因在肝癌组织和癌周肝组织中的表达有极显著差异（Ｐ＜０．０１）。１０例样品中，７例肝癌组织中ＨＳＵ１７７１４ｍＲＮＡ表达显著高于癌周肝组织，２例在两种组织中的表达无差异，１例在癌周组织中ＨＳＵ１７７１４ｍＲＮＡ表达略高于肝癌组织。该实验结果表明ＨＳＵ１７７１４基因表达与肝癌有显著相关性，进一步探索其功能对开展肝癌基因治疗具有研究价值
Dot blot was used to compare the mRNA expression of HSU17714 gene in 10 cases of human primary hepatocellular carcinoma and hepatic tissue. The results showed that there was a significant difference in the expression of HSU17714 gene between hepatocellular carcinoma and hepatic tissue (P<0.01). Of the 10 samples, the expression of HSU17714 mRNA in 7 cases of HCC was significantly higher than that in the surrounding tissues of the cancer, and there was no difference in the expression of HSU17714 mRNA between the two tissues. The expression of HSU17714 mRNA was slightly higher in HCC tissues than in HCC tissues in 1 case. The experimental results show that HSU17714 gene expression has significant correlation with liver cancer, and further exploration of its function has a research value for the gene therapy of liver cancer.