论文部分内容阅读
[目的]观察急性冠脉综合征介入术前应用他汀类药物强化治疗的影响及效果。[方法]选择56例急性冠脉综合征患者,随机将其分为2组,强化组和常规组,两组术前10d给予阿伐他汀20mg口服,强化组手术当日给予阿伐他丁80mg,常规组则仍给予20mg,术后两组继续应用阿伐他丁20mg。测定术前及术后1d,5d及10d血清中C反应蛋白及血脂水平。[结果]2组患者间术后血脂均未见明显变化,2组间相比及2组与术前相比差异均无统计学意义。强化组术后1d、5d、10d其C反应蛋白均较常规组低(P﹤0.05)。[结论]他丁类药物不仅有降脂作用,其抗炎作用也是很明显的。
[Objective] To observe the effect and effect of intensive statin treatment before acute coronary syndrome (ACS) intervention. [Methods] Fifty-six patients with acute coronary syndrome were randomly divided into 2 groups: intensive group and routine group. Both groups received ovastatin 20 mg orally 10 days before operation and atorvastatin 80 mg on the day of intensive operation. The conventional group is still given 20mg, two groups continue to use atorvastatin 20mg. Serum C-reactive protein and serum lipid levels were measured before and 1, 5 and 10 days after operation. [Results] There was no significant change in postoperative blood lipids between the two groups. There was no significant difference between the two groups in comparison with the preoperative level. The levels of C-reactive protein in the intensive group at 1 day, 5 days and 10 days after operation were significantly lower than those in the conventional group (P <0.05). [Conclusion] Histidine not only has lipid-lowering effect, but also its anti-inflammatory effect is obvious.