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目的探讨循证护理模式在重组人血小板生成素治疗重型再生障碍性贫血患者中应用效果。方法选取医院收治的重型再生障碍性贫血(SAA)患者100例作为研究对象,入院后均予以免疫抑制剂治疗(IST)联合重组人血小板生成素(rh TPO),采用数字随机对照表将患者分为对照组和观察组,对照组予以常规护理,观察组予以循证护理,行生活质量评分(SF-36),记录两组干预前后血小板计数(PLT)、中性粒细胞(NEUT)恢复情况,对比两组感染率、出血率。结果观察组护理后NEUT为(56.29±10.35)%显著高于对照组(P<0.05);观察组护理后感染率和出血率分别为23.33%、10.0%均显著低于对照组(P<0.05);观察组护理后躯体因子、情绪状态、疼痛情况、心理维度等评分均显著高于对照组(P<0.05)。结论循证护理模式降低了AA患者感染率和和出血率,提高生活质量。
Objective To explore the effect of evidence-based nursing in the treatment of patients with severe aplastic anemia by recombinant human thrombopoietin. Methods 100 hospitalized patients with severe aplastic anemia (SAA) were enrolled in this study. All patients were treated with immunosuppressive therapy (IST) and recombinant human thrombopoietin (rh TPO) after admission. The patients were divided into two groups according to randomized controlled trials The control group and the control group were given routine nursing. The observation group was given evidence-based nursing and the quality of life score (SF-36). The platelet count (PLT), neutrophil recovery (NEUT) Compare the two groups infection rate and bleeding rate. Results The postoperative rate of NEUT in the observation group was significantly higher than that in the control group (56.29 ± 10.35% vs 23.33%, 10.0%, P <0.05) ). The scores of somatological factors, emotional status, pain and psychological dimension in the observation group were significantly higher than those in the control group (P <0.05). Conclusion Evidence-based care reduces the infection rate and bleeding rate in AA patients and improves the quality of life.