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目的:探讨呼吸机治疗急性重症有机磷中毒(AOPP)呼吸衰竭的临床疗效。方法:选择我院2012年1月至2013年12月收治的40例AOPP呼吸衰竭患者为研究对象,在洗胃、抗感染、利尿等常规治疗的基础上对所有患者行呼吸机治疗,观察临床救治效果、住院时间,同时比较呼吸机治疗前后动脉血氧分压(PaO2)、动脉血氧饱和度(SaO2)水平。结果:40例患者中治愈36例(90%),死亡4例(10%);平均上机时间(45.2±2.5)h,平均住院时间(11.5±2.1)d。其中36例患者治疗后PaO2、SaO2水平较治疗前明显上升,P<0.05,有显著性差异,有统计学意义。结论:呼吸机治疗AOPP呼吸衰竭效果明显,能有效改善患者动脉血氧饱和度,临床抢救成功率较高。
Objective: To investigate the clinical efficacy of ventilator in the treatment of acute severe organophosphorus poisoning (AOPP) respiratory failure. Methods: Forty AOPP patients with respiratory failure who were treated in our hospital from January 2012 to December 2013 were enrolled in this study. All patients were treated with ventilator on the basis of routine therapy such as gastric lavage, anti-infective and diuretic, The therapeutic effect and hospitalization time were compared. The PaO2 and SaO2 were compared before and after treatment. Results: Among the 40 patients, 36 cases were cured (90%) and 4 died (10%). The average time on board (45.2 ± 2.5) h and the mean hospital stay (11.5 ± 2.1) days were statistically significant. 36 patients after treatment PaO2, SaO2 levels were significantly increased compared with before treatment, P <0.05, there was a significant difference, statistically significant. Conclusion: The ventilator is effective in treating AOPP respiratory failure and can effectively improve the arterial oxygen saturation of patients. The success rate of clinical rescue is high.