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The study of anti-corruption at National University of Laos (NUOL) aims at firstly investigating the understandings of the phenomena, means, locus and interaction of corruption; secondly examining the effectiveness of the availability legislation on anti-corruption;thirdly identifying the problematic issues and challenges on anti-corruption implementation or law enforcement practices at the National University of Laos (NUOL). The quantitative research methodology was employed. The cluster sampling size was used with total of 155 respondents: top-management, middle-management, junior management and academia. The statistical descriptive data analysis was used.