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目的 :探讨大面积不规则野照射与累及野照射对非霍奇金淋巴瘤 (non Hodgkinlymphoma ,NHL)的疗效。方法 :对大面积不规则野照射 (2 0例 ) +化疗与累及野照射 (2 0例 ) +化疗治疗NHL的疗效进行前瞻性随机分组治疗。结果 :两组患者的 5年生存率、近期急性反应及局控率基本相同 ,而累及野远期后遗效应则少于大面积野。结论 :对NHL的治疗 ,累及野照射与大面积照射的疗效相似 ,但累及野照射的远期放射并发症明显降纸。
Objective: To investigate the effect of large-area irregular wild-field irradiation and invasive field irradiation on non-Hodgkin lymphoma (NHL). Methods: Prospective randomized treatment was performed on the effects of large-area Irregular Irradiation (20 cases)+chemotherapy and Invasive Irradiation (20 cases)+chemotherapy for NHL. Results: The 5-year survival rate, short-term acute response and local control rate were basically the same in the two groups, while the long-term residual effects were less than the large area. Conclusion : In the treatment of NHL, the effect of invasive field irradiation is similar to that of large area irradiation, but the long-term radiation complications involving the field irradiation are significantly reduced.