颗粒细胞瘤是一种少见肿瘤,目前认为其来源于雪旺细胞,且好发于皮肤、舌等组织。发生于消化道的颗粒细胞瘤非常少见,占所有颗粒细胞瘤的8%~10%[1],而其中又以食管最为多见,但食管颗粒细胞瘤合并上皮病变罕见。本文报道1例食管微小颗粒细胞瘤合并鳞状上皮假上皮瘤样增生的患者,并结合文献讨论其病理学特征。病例:患者女,58岁,因胃部不适至我院就诊并行胃镜检查。于患者食管距门齿约23 cm处见一大小为0.2 cm× Granulosa cell tumor is a rare tumor, which is currently believed to originate from Schwann cells, and occurs in the skin, tongue and other tissues. Occurred in the digestive tract of granulosa cell tumor is very rare, accounting for 8% to 10% of all granular cell tumor [1], of which esophageal most common, but with esophageal granulosa cell tumor epithelial lesions rare. This article reports a case of esophageal small granular cell tumor with squamous pseudopothelioma-like hyperplasia patients, combined with the literature to discuss the pathological features. Case: Female patient, 58 years old, due to stomach up to our hospital for gastroscopy. In patients with esophageal incisors about 23 cm at a size of 0.2 cm ×