论文部分内容阅读
目的研究宣威与非宣威地区非小细胞肺癌P63蛋白的表达,探讨其与生物学行为的关系。方法免疫组织化学法。结果 P63蛋白在肺鳞癌组织中高表达;非小细胞肺癌中,P63蛋白的表达与患者的TNM分期、组织分化程度及淋巴结转移情况有关,与患者性别无关;P63蛋白在非小细胞肺癌中在相同病理类型、分期、组织分化、淋巴结转移情况及相同性别的阳性表达率,宣威组与非宣威组比较,差异无统计学意义。结论 P63蛋白的表达在宣威并无地区特异性,并不是宣威肺癌高发的原因。
Objective To study the expression of P63 protein in non-small cell lung cancer in Xuanwei and non-Xuanwei areas and to explore its relationship with biological behavior. Methods Immunohistochemistry. Results P63 protein was highly expressed in squamous cell carcinoma of the lung. In non-small cell lung cancer, the expression of P63 protein was related to the TNM stage, histological differentiation and lymph node metastasis, but not to the gender of the patient. The expression of P63 in non-small cell lung cancer The same pathological type, stage, differentiation, lymph node metastasis and the same sex the positive expression rate, Xuanwei group and non-Xuanwei group, the difference was not statistically significant. Conclusion The expression of P63 protein is not region-specific in Xuanwei and is not the cause of high incidence of lung cancer in Xuanwei.