论文部分内容阅读
目的:观察氨氯地平联合阿托伐他汀治疗原发性高血压病的疗效。方法:原发性高血压病患者48例随机分为观察组和对照组,对照组单用氨氯地平5mg·d~(-1),,观察组服用氨氯地平5mg·d~(-1)和阿托伐他汀10mg·d~(-1)。治疗3个月,观察患者的血压,血脂和C反应蛋白。结果:治疗后两组患者血压均较治疗前降低,观察组患者血压下降更明显(P<0.001);观察组治疗后血脂和CRP较治疗前显著降低(P<0.001),而对照组治疗前后无明显变化。观察组降压有效率88.0%高于对照组的78.3%(P<0.01)。结论:氨氯地平联合阿托伐他汀治疗高血压降压效果较单独使用氨氯地平好。
Objective: To observe the efficacy of amlodipine combined with atorvastatin in the treatment of essential hypertension. Methods: Forty-eight patients with essential hypertension were randomly divided into observation group and control group. The control group was treated with amlodipine 5 mg · d -1 only. The observation group was treated with amlodipine 5 mg · d -1 ) And atorvastatin 10 mg · d ~ (-1). Treatment for 3 months, observe the patient’s blood pressure, blood lipids and C-reactive protein. Results: After treatment, the blood pressure in both groups decreased compared with that before treatment, and the decrease of blood pressure in the observation group was more obvious (P <0.001). The blood lipid and CRP in the observation group were significantly lower than those before treatment (P <0.001) No significant changes. The effective rate of lowering blood pressure in observation group was 88.0% higher than 78.3% in control group (P <0.01). Conclusion: Amlodipine and atorvastatin are more effective than amlodipine in the treatment of hypertension.