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目的研究白及治疗对小儿前臂骨骺骨折闭合复位术后机体炎症应激反应的影响。方法将2012年4月至2014年4月期间我院收治的100例小儿前臂骨骺骨折患者纳入研究,采用随机数表将入组者分为两组,观察组患者接受手法复位夹板外固定联合白及内服治疗,对照组患者接受手法复位夹板外固定联合常规支持治疗,比较两组患者炎症反应和应激反应程度。结果治疗后1周时,观察组患者的IL-6、IL-8、TNF-α以及皮质醇、肾上腺素、去甲肾上腺素水平低于对照组,差异有统计学意义(P驥0.05)。结论白及治疗有助于缓解机体的炎症和应激反应,是小儿前臂骨骺骨折闭合复位术后理想的治疗方法。
Objective To study the effect of Bai and treatment on the inflammatory response in the body after closed reduction of pediatric epiphyseal fracture in children. Methods 100 pediatric patients with epiphyseal fractures of pediatric forearm admitted to our hospital from April 2012 to April 2014 were enrolled in the study. The random number table was used to divide the patients into two groups. The patients in the observation group underwent manual reduction combined with plaster external fixation The patients in the control group received manual reduction and external fixation combined with routine supportive therapy. The inflammatory response and the degree of stress response in the two groups were compared. Results One week after treatment, the levels of IL-6, IL-8, TNF-α, cortisol, epinephrine and norepinephrine in the observation group were lower than those in the control group (P <0.05). Conclusion Baihe treatment can relieve the inflammation and stress response in the body. It is an ideal treatment for closed forearm epiphyseal fracture in children.