肿瘤免疫逃逸成为当今有效肿瘤免疫治疗的主要障碍 ,树突细胞 (DC)在抗肿瘤免疫应答过程中发挥重要作用。荷瘤宿主中的T细胞在能够识别并对肿瘤抗原作出反应的情况下仍不能组织起有效免疫应答 ,其主要原因之一在于 :肿瘤微环境阻止了肿瘤内DC有效的抗原提呈。鉴于DC在免疫应答 Tumor immune escape has become a major obstacle to effective tumor immunotherapy today, and dendritic cells (DCs) play an important role in the anti-tumor immune response. T cells in tumor-bearing hosts fail to organize an effective immune response when they recognize and respond to tumor antigens. One of the major reasons for this is that the tumor microenvironment prevents efficient antigen presentation within the tumor. Given the immune response of DCs