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前列腺特异膜抗原(PSMA)靶向PET显像是一种新兴的前列腺癌显像方法,其灵敏度和特异性一定程度上优于传统影像,PSMA配体也优于其他目前常用的PET显像剂。PSMA PET显像的应用范围主要包括肿瘤定位、局部分期、生化复发与转移的检测、指导治疗方案的选择等。目前被广泛研究的基于PSMA的PET显像剂主要是n 68Ga或n 18F标记化合物,该文将对前列腺癌PSMA PET相关显像剂进行综述。n “,”Prostate specific membrane antigen (PSMA) targeting PET is a new imaging method for prostate cancer. Its sensitivity and specificity are better than traditional imaging methods to some extent, and PSMA ligands are also better than other commonly used PET imaging agents. The application of PSMA PET imaging mainly includes tumor localization, local staging, detection of biochemical recurrence and metastasis, and guidance for the choice of therapy. Currently, PET tracers based on PSMA are mainly n 68Ga or n 18F labeled compounds. This article reviews these related imaging agents.n