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胃癌是全球性常见的恶性肿瘤。胃癌是一种异质性疾病包括多种类型,每种类型都有不同的生物学特性和作用。因此,基于临床特点,病理分型,分子分型的个体化治疗对进展期胃癌尤为重要。现有的胃癌分子分型可归类为Shah分型,Tan基因分型,新加坡基因分型,TCGA基因分型和ACRG基因分型。从分子生物学创立引起肿瘤治疗模式的变化,从分子水平重新认识疾病,未来的肿瘤治疗模式可能是分子分型指导的个体化治疗。
Gastric cancer is a common malignancy in the world. Gastric cancer is a heterogeneous disease that includes many types, each of which has different biological properties and effects. Therefore, individualized treatment based on clinical features, pathological typing and molecular typing is particularly important for advanced gastric cancer. Existing gastric cancer molecular typing can be classified as Shah typing, Tan genotyping, Singapore genotyping, TCGA genotyping and ACRG genotyping. Starting from the molecular biology of cancer therapy caused by changes in the model to re-recognize the molecular level of disease, the future model of cancer treatment may be the individualized treatment of molecular typing guidance.