论文部分内容阅读
最佳的皮肤创口愈合过程依赖于新组织形成与再塑阶段胶原蛋白合成与溶解的平衡。研究发现细胞吞噬作用受体uP ARAP在调控胶原蛋白的摄取与细胞内溶解方面发挥着重要作用,固猜测其在伤口愈合方面发挥一定的作用。本实验通过构造uP ARAP缺陷(uP ARAP-/-)小鼠并观察其皮肤伤口的愈合情况来探索uP ARAP在皮肤伤口愈合中的作
Optimal skin wound healing depends on the balance of collagen synthesis and lysis during neo-tissue formation and remodeling. The study found that uP ARAP, a phagocytosis receptor, plays an important role in the regulation of collagen uptake and intracellular lysis, and Guess plays a role in wound healing. This study explored the role of uP ARAP in skin wound healing by constructing uP ARAP deficient (uP ARAP - / -) mice and observing the healing of their skin wounds