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项目来源:国家“863”计划项目(2011AA100604)承担单位:武汉大学负责人:杨代常研究时间:2011-2015年项目简介人血清白蛋白是我国紧缺的一线大宗临床药物,具有巨大市场前景。本项目利用水稻种子生物反应器技术平合,建立了种子生物反应器高效表达技术平台OryzH’ExP和重组蛋白规模化生产工艺和流程及其技术标准,解决植物生物反应器的表达量低、纯化复杂和规模化困难等技术难题,并表达了一批具有自主知识产权的技术和产
Project Source: National 863 Project (2011AA100604) Undertaken by: Wuhan University Principal: Yang Dai Chang Duration: 2011-2015 Project Profile Human serum albumin is a shortage of first-line bulk clinical drugs in China, with a huge market prospect. In this project, OryzH’ExP, a scale production technology and process of recombinant protein, and a technical standard for high-performance expression of seed bioreactor were established by using the technology of rice seed bioreactor to solve the problem of low expression and purification of plant bioreactor Complex and large-scale difficulties and other technical problems, and expressed a number of independent intellectual property rights of technology and production