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目的:探讨下颌渐进性后退对髁突软骨(MCC)厚度的影响。方法:应用自行设计的后牙双斜面导板矫治器(TIPD),引导6周龄大鼠下颌“渐进式”后退。髁突软骨区经常规脱钙、包埋和HE染色后,观察实验组和对照组大鼠在3,14,30,60d髁突软骨厚度的变化。结果:3d和14d,TIPD实验组和对照组在所有区域的MCC厚度没有明显差异。30d,TIPD组的MCC厚度在后区的后部(Pp)比对照组薄(P<0.05),到60d时,Pp部变得更薄(P<0.01),肥大层几乎消失。相反,从30d开始,后区的前部(Pa)MCC厚度在TIPD组较厚。60d,前区的中部(Am)MCC厚度在TIPD组较薄(P<0.01)。结论:TIPD戴用期间能引起髁突软骨不同区域产生不同的改建,且呈持续性。
Objective: To investigate the effect of mandibular progressive retraction on condylar cartilage (MCC) thickness. Methods: The self - designed posterior teeth double bevel guide (TIPD) was used to guide the mandible of 6 weeks old rats to retreat gradually. Condylar cartilage area by routine decalcification, embedding and HE staining, the experimental group and the control group rats at 3,14,30,60 d condylar cartilage thickness changes. Results: At 3d and 14d, there was no significant difference in MCC thickness between TIPD experimental group and control group in all regions. At 30 days, the thickness of MCC in the TIPD group was thinner than that in the control group (P <0.05). At 60 days, the Pp portion became thinner (P <0.01) and the hypertrophic layer almost disappeared. In contrast, the anterior (Pa) MCC thickness of the posterior region was thicker in the TIPD group starting from 30d. At 60 days, MCC thickness in the anterior region was thinner in the TIPD group (P <0.01). CONCLUSION: TIPD can cause different remodeling of condylar cartilage in different areas during wearing, and it is persistent.