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目的探讨老年慢性心力衰竭患者cTnI、hs-CRP、NT-ProBNP的变化及其预后评估价值。方法选取2015年1月-2016年2月本院收治的76例老年慢性心力衰竭患者作为观察组,参照美国纽约心脏病协会(NYHA)心功能分级方案可分为Ⅰ级10例,Ⅱ级25例,Ⅲ级26例,Ⅳ级15例,另选取同期本院健康体检者50例作为对照组,比较2组cTnI、hs-CRP、NT-ProBNP水平,对观察组患者出院后随访1年,观察患者心血管事件的发生情况。结果观察组cTnI、hs-CRP及NT-ProBNP水平均高于对照组;Ⅰ级、Ⅱ级、Ⅲ级、Ⅳ级心功能患者的cTnI、hs-CRP及NT-ProBNP水平逐渐升高;19例患者发生心血管事件,55例患者未发生心血管事件,另有2例失访,发生心血管事件组的cTnI、hs-CRP及NT-ProBNP水平均高于未发生心血管事件组,以上差异均有统计学意义(P<0.05)。结论 cTnI、hs-CRP及NTProBNP能够较好地反映老年慢性心力衰竭患者的心功能,对病情及预后评估具有重要参考价值。
Objective To investigate the changes of cTnI, hs-CRP and NT-ProBNP in elderly patients with chronic heart failure and their prognostic value. Methods A total of 76 elderly patients with chronic heart failure admitted to our hospital from January 2015 to February 2016 were selected as the observation group. According to the New York Heart Association (NYHA) classification of cardiac function, 10 cases of grade Ⅰ, The patients in the observation group were followed up for 1 year after discharge from the hospital. The patients in the observation group were followed up for 1 year after discharge, Observe the occurrence of cardiovascular events in patients. Results The levels of cTnI, hs-CRP and NT-ProBNP in the observation group were higher than those in the control group. The levels of cTnI, hs-CRP and NT-ProBNP in patients with grade Ⅰ, Ⅱ, There were no cardiovascular events in 55 patients and two patients were lost to follow-up. The levels of cTnI, hs-CRP and NT-ProBNP in patients with cardiovascular events were significantly higher than those without cardiovascular events All were statistically significant (P <0.05). Conclusion cTnI, hs-CRP and NTProBNP can better reflect the heart function of elderly patients with chronic heart failure, and have important reference value for the evaluation of disease and prognosis.