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目的:观察中西医结合治疗骨质疏松症的临床疗效。方法:选取96例骨质疏松症患者作为研究对象,根据治疗方法不同分为2组,2组均给予耳穴压豆疗法、足三里疗法、注射鲑降钙素注射液、服用阿仑膦酸钠片治疗,观察组54例给予益肾壮骨汤内服联合中药熏蒸治疗,对照组42例单用益肾壮骨汤治疗。比较2组的骨密度、生化指标[β-I型胶原羧基端肽(β-CTX)、碱性磷酸酶(ALP)、骨钙素(BGP)]与临床疗效。结果:观察组治疗总有效率为94.44%,相对于对照组的80.95%有明显上升(P<0.05)。治疗后,2组腰椎、全髋、股骨颈骨密度均较治疗前上升(P<0.05),观察组3个部位的骨密度值均高于对照组(P<0.05)。2组β-CTX、ALP均较治疗前下降,BGP均较治疗前上升,观察组各项指标改善情况均优于对照组,差异均有统计学意义(P<0.05)。结论:中西医结合治疗骨质疏松症疗效显著,可有效提高患者的骨密度,改善骨代谢指标。
Objective: To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of osteoporosis. Methods: Ninety-six patients with osteoporosis were enrolled in this study. The patients were divided into two groups according to the different treatment methods. The two groups were given ear acupuncture pressure bean therapy, Zusanli therapy, salmon calcitonin injection and alendronate In the observation group, 54 cases were treated with Yishen Zhuanggu decoction combined with traditional Chinese medicine fumigation, and 42 cases in the control group were treated with Yishen Zhuanggu decoction alone. The bone mineral density (BMD), biochemical indicators (β-CTX, ALP, BGP) were compared between two groups. Results: The total effective rate of the observation group was 94.44%, which was significantly higher than that of the control group (80.95%) (P <0.05). After treatment, the BMD of lumbar spine, total hip and femoral neck in both groups were significantly higher than those before treatment (P <0.05). The BMD of three sites in the observation group were higher than those in the control group (P <0.05). The β-CTX and ALP in 2 groups decreased compared with that before treatment, while BGP increased compared with that before treatment. The improvement of each index in observation group was better than that in control group (P <0.05). Conclusion: Integrative treatment of osteoporosis significant effect, can effectively improve the patient’s bone mineral density, improve bone metabolism indicators.