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1965～1979年,23个单位用甘磷酰芥全身及局部给药法治疗301例肿瘤病人,完全缓解17例,部分缓解119例,有效率45.2％;口服对恶性淋巴瘤、乳腺癌和肺小细胞癌有效,对子宫肉瘤、白血病等也有一定疗效;喷敷或涂抹对乳腺癌等癌性溃疡效果显著。其主要毒性为消化道反应及骨髓抑制。影响疗效因素是病理类型、既往治疗、给药剂量及骨髓抑制与否。
From 1965 to 1979, 23 units were treated with whole body and topical administration of glyphosate in 301 patients with tumor, with complete remission in 17 cases and partial remission in 119 cases, with an effective rate of 45.2%. Oral administration on malignant lymphoma, breast cancer and lung Small cell carcinoma effective, uterine sarcoma, leukemia, also have a certain effect; spray or smear on breast cancer and other significant effects of cancer ulcer. The main toxicity of gastrointestinal reactions and bone marrow suppression. Factors affecting the efficacy of the pathological type, previous treatment, dose and bone marrow suppression or not.