鉴于细菌内毒素无处不存,且在浓度很低时即可产生生理活性,所以建立一个既敏感又特异的细菌内毒素检测法势在必行。许多试验结果证明鲎法是检测细菌内毒素最敏感的方法,且它与致热原性,对鸡胚致死性,促细胞分裂性,皮肤Shwartzman反应等其 Since bacterial endotoxins are ubiquitous and physiologically active at very low concentrations, it is imperative to establish a sensitive and specific bacterial endotoxin assay. Numerous test results show that nimotopes is the most sensitive method for detecting bacterial endotoxins, and its interaction with pyrogenogenicity, lethality to chick embryo, mitogenicity, and skin Shwartzman reaction