缺血性心脏病包括粥样硬化病变引致的冠状动脉梗阻或狭窄,可导致心绞痛、心力衰竭、心律失常等临床症状,是引起死亡的主要原因。尽管溶栓等药物治疗、支架的植入和心脏移植等方面取得了很大的进展,但前两种方法仅能改善心肌缺血,并不能有效治疗疾病或改善预后,而心脏移植更是会出现移植排斥反应。近一半的心衰患者会在诊断后五年内死亡。以往的传统观念认为心肌细 Ischemic heart disease, including atherosclerosis caused by coronary artery obstruction or stenosis, can lead to angina pectoris, heart failure, arrhythmia and other clinical symptoms, is the leading cause of death. Despite great advances in drug treatment such as thrombolysis, stent implantation and heart transplantation, the first two methods only improve myocardial ischemia, which can not effectively treat the disease or improve the prognosis, Transplant rejection occurred. Nearly half of patients with heart failure will die within five years of diagnosis. The traditional concept of the past that myocardial thin