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目的:分析恶性淋巴瘤住院患者的分布特征,为制订淋巴瘤防控策略提供科学依据。方法:采用以医院为基础的肿瘤登记(HCR)方法,从平台筛选出南通市肿瘤医院2002年至2017年恶性淋巴瘤住院患者资料,以来源于南通地区7个市、区、县的患者为研究对象,进行分组描述,包括亚部位(亚型)、性别、年龄、入院年份、患者来源(户籍)等观察指标。结果:恶性淋巴瘤住院患者数从2002年95例增加至2017年243例,住院患者数总体呈逐年上升趋势。2 361例恶性淋巴瘤患者共产生10 260例次住院记录,每例患者平均住院4.35次。恶性淋巴瘤占同期全部恶性肿瘤(74 448例)的3.17%。男性1 382例(58.53%),女性979例(41.47%),性别比为1.41∶1。根据恶性淋巴瘤国际疾病分类,霍奇金淋巴瘤(HL)119例(5.04%),非霍奇金淋巴瘤(NHL)2 108例(89.28%),多发性骨髓瘤(MM)134例(5.68%)。恶性淋巴瘤患者分布于各个年龄段,呈负偏态分布:首次入院的中位年龄为61.00岁;在45~49岁组显著上升,在65~69岁组达到高峰。按住院患者来源,来自启东市137例(5.80%),海安市153例(6.48%),海门市185例(7.84%),如东县391例(16.56%),南通市区437例(18.51%),如皋市508例(21.52%),通州区550例(23.30%)。在恶性淋巴瘤患者中未见常规检测项目如Rh血型系统、乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)及人类免疫缺陷病毒(HIV)指标的异常情况。结论:南通地区恶性淋巴瘤住院患者有增多趋势,男性患者占比高于女性。恶性淋巴瘤中NHL为主要亚型,其次为MM,HL占比最低。患者来源的地区分布可能与服务半径和范围有关。“,”Objective:To analyze the distribution characteristics of inpatients with malignant lymphoma in order to provide scientific basis for formulating the prevention and control strategies of lymphoma.Methods:Hospital-based cancer registration (HCR) method was employed, and the data of malignant lymphoma cases among inpatients in Nantong Tumor Hospital from 2002 to 2017 were screened from the platform. Patients from 7 cities, districts and counties in Nantong area were used as the research objects and were described in groups, including the site (subtype), gender, age, year of admission, patient source (household registration), etc.Results:The number of hospitalized cases of malignant lymphoma increased from 95 cases in 2002 to 243 cases in 2017, and the number of hospitalized patients showed an overall upward trend year by year. Two thousand three hundred and sixty one patients with malignant lymphoma had 10 260 person-times inpatient records, with an average of 4.35 admissions per person. Malignant lymphoma accounted for 3.17% of all malignant tumors (74 448 cases) during the same period, in which 1 382 patients (58.53%) were males and 979 patients (41.47%) were females, with a sex ratio of 1.41∶1. According to the international disease classification of malignant lymphoma, there were 119 cases (5.04%) of Hodgkin lymphoma (HL), 2 108 cases (89.28%) of non-Hodgkin lymphoma (NHL), and 134 cases (5.68%) of multiple myeloma (MM). Malignant lymphoma patients were distributed in various age groups, showing a negative skew distribution: the median age at first admission was 61.00 years old; it rose significantly in the 45-49 age group, and reached a peak in the 65-49 age group. According to the source of hospitalized patients, 137 patients (5.80%) were from Qidong city, 153 patients (6.48%) were from Hai'an city, 185 patients (7.84%) were from Haimen city, 391 patients (16.56%) were from Rudong county, 437 patients (18.51%) were from Nantong city, 508 patients (21.52%) were from Rugao city, and 550 patients (23.30%) were from Tongzhou district. Abnormal lab indexes (infection states) such as Rh blood group system, hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) were not found in these inpatients with malignant lymphoma.Conclusions:An uptrend for malignant lymphoma is observed in hospitalized patients in Nantong area, with a relative dominance in males than in females. NHL is the main subtype of malignant lymphoma, followed by MM, and HL accounts for the lowest proportion. The regional distribution of patient sources may be related to the medical service radius and scope.