急性颅脑损伤患者血清炎症因子的动态变化及临床意义

来源 :实用临床医药杂志 | 被引量 : 0次 | 上传用户:wpe2727
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目的观察急性颅脑损伤患者血清C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)、白细胞介素(IL)-6、IL-8水平的动态变化。方法 80例急性颅脑损伤患者根据入院时格拉斯哥昏迷量表评分(GCS)分为2组:GCS≤8分者为A组,GCS9~12分者为B组,各40例。检测并比较2组入院1 d、7 d、14 d的血清CRP、TNF-α、IL-6及IL-8水平。结果 2组血清CRP、TNF-α、IL-6及IL-8表达水平均呈现出先升高再降低的趋势,不同时间点之间差异有统计学意义(P〈0.05或P〈0.01);组
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